A custom field is made Read only from the Field level security and Required from Page layout.
The Field will be:
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A. B. C. D.A.
If a custom field is made Read Only from the Field level security and Required from Page layout, the field will be Required for the user.
Here's why:
Option A (Read Only for the user) is not correct because the field is set to Required in the page layout, which means the user must fill it out. Option C (Throws an error and doesn't allow making a Read only field Mandatory from page layout) is also not correct because there is no conflict between making a field Read Only from field level security and Required from page layout. Option D (User is given a choice in a pop-up window) is not correct because there is no option for the user to choose. The field is Read Only, and the user must fill it out in order to save the record, as it is Required in the page layout.